A computational model of the DNA damage-induced IKK/ NF-κB pathway reveals a critical dependence on irradiation dose and PARP-1
Fabian Konrath, Michael Willenbrock, Dorothea Busse, Claus Scheidereit, Jana Wolf
The paper develops a computational model of the DNA damage-induced IKK/NF-κB pathway to analyze how irradiation dose and PARP-1 influence pathway activation.
iScience · Sep 13, 2023Peer-reviewedSystems Biology