Cell BiologybioRxivPreprint
Obesity modifies cell fate plasticity of Pdgfrα-expressing adipocyte progenitors to promote an aberrant mammary microenvironment
Sharon A. Kwende, Prashant Nuthalapati, Jacqulene P. Sunder Singh…·Purna A. Joshi
This study identifies obesity-induced changes in PDGFRα-expressing adipocyte progenitors that promote a cancer-susceptible mammary microenvironment through EGFR-mediated pathways.