Silk fibroin as a modulator of the amyloidogenic α-synuclein aggregation
Marco Elvino Miali, Yoav Barak, Yael Fridmann-Sirkis, Irit Rosenhek‐Goldian, Ori Brookstein, Dror Eliaz, Ulyana Shimanovich
This study shows that silk fibroin inhibits α-synuclein amyloid aggregation through structural and kinetic modifications, increasing susceptibility to enzymatic degradation.
bioRxiv · Oct 25, 2025 · PreprintBiochemistry