Yoav Barak

A Stochastic Mechanism Drives Fast Substrate Translocation in the AAA+ Machine ClpB

The paper uses single-molecule FRET to show ClpB translocates substrates rapidly and stochastically, challenging previous models of ATP-driven mechanical work.

Refractive index as an indicator for dynamic protein condensation in cell nuclei

This study uses refractive index mapping to detect dynamic protein condensation in cell nuclei, showing it is sensitive to reversible condensation and reveals differences from fluorescence-based methods.

Silk fibroin as a modulator of the amyloidogenic α-synuclein aggregation

This study shows that silk fibroin inhibits α-synuclein amyloid aggregation through structural and kinetic modifications, increasing susceptibility to enzymatic degradation.

Autonomous biogenesis of the entire protein translation machinery excluding ribosomes

The paper demonstrates autonomous biogenesis of the entire protein translation machinery excluding ribosomes by using surface-immobilized DNA brushes to catalyze and concentrate the synthesis of all required components.

A genetic circuit on a single DNA molecule as autonomous dissipative nanodevice

The paper demonstrates a single DNA molecule-based genetic circuit that functions as a dissipative nanodevice by enabling coexpressional localization of proteins.