A systems approach to the characterization and classification of T-cell responses
Shinobu Yamamoto, Elizabeth Whalen, Daisuke Chujo, Durgha Nattamai, Nicole E. Baldwin, Kimberly O’Brien, Quynh‐Anh Nguyen, Vivian H. Gersuk, Esperanza Anguiano, Junbao Yang, William W. Kwok, Jacques Banchereau, Hideki Ueno, Damien Chaussabel
The paper develops a systems-based approach to classify T-cell responses using transcriptome data from PBMCs stimulated with peptides, identifying new molecular patterns and transcription factors involved in antigen-specific responses.
bioRxiv · Aug 13, 2017 · PreprintGenomics