Identification and Validation of Small Molecules with Mucin-Selective Regiospecific Binding in the Gastrointestinal Tract
Deepak A. Subramanian, Ameya R. Kirtane, Georgia N. White, Dylan E. Freitas, Keiko Ishida, J. A. Jenkins, Andrew Pettinari, Joshua Morimoto, Nina J. Fitzgerald, Giovanni Traverso
This study identifies small molecules that selectively bind to mucins in the gastrointestinal tract, enhancing localized drug delivery to the small intestine and stomach.
Biomaterials · Dec 5, 2025Peer-reviewedBioengineering