A Crossed Laser Phase Plate for CryoEM
Yue Eric Yu, Anchi Cheng, Elizabeth A. Montabana, Noeli Paz Soldán, Eric S. Cooper, Jessie T. Zhang, Jeremy J. Axelrod, Petar N. Petrov, Amir Torkaman, Dylan Roof, Matthew W. Derstine, Bart Buijsse, Wim J. H. Hagen, Dari Kimanius, Shawn Q. Zheng, , Pavel K. Olshin
This paper introduces a crossed laser phase plate (xLPP) for cryoEM, demonstrating improved contrast and resolution in imaging biological samples.
bioRxiv · Jun 5, 2026 · PreprintBiophysics