Intussusceptive angiogenesis-on-a-chip: Evidence for transluminal vascular bridging by endothelial delamination
Sabrina C. R. Staples, Hao Ran Yin, Frances S. K. Sutherland, Emma K. Prescott, Dylan Tinney, Douglas William Hamilton, Daniel Goldman, Tamie L. Poepping, Christopher Gerald Ellis, J. Geoffrey Pickering
This paper demonstrates that endothelial cells can delaminate from a vessel wall to form transluminal bridges, enabling intussusceptive angiogenesis, using a microvessel-on-a-chip model.
Proceedings of the National Academy of Sciences · Apr 17, 2025Peer-reviewedPhysiology