Hypoxia responses in arginase 2 deficient mice enhance cardiovascular health
Weiling Xu, Kewal Asosingh, Allison J. Janocha, Evan Madden, Nicholas Wanner, Dylan Trotter, Michael Novotny, Anny Mulya, Samar Farha, SERPIL CEM ERZURUM
This study shows that deleting arginase 2 in mice improves cardiovascular health under chronic hypoxia by increasing nitrite and arginine levels while reducing pulmonary hypertension.
bioRxiv · Feb 20, 2025 · PreprintPhysiology