The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor
E. A. Coe, J. Y. Tan, M. Shapiro, P. Louphrasitthiphol, A. R. Bassett, A. C. Marques, C. R. Goding, K. W. Vance
This study identifies DIRC3, a MITF-SOX10 regulated lncRNA, as a tumour suppressor in melanoma that promotes survival by modulating chromatin structure and IGFBP5 expression.
bioRxiv · Mar 27, 2019Cancer Biology