Commensal-derived succinate enhances tuft cell specification and suppresses ileal inflammation
A. Banerjee, C. A. Herring, H. Kim, B. Chen, A. J. Simmons, A. N. Southard-Smith, J. R. White, M. A. Ramirez Solano, E. A. Scoville, Q. Liu, M. K. Washington, K. S. Lau
The paper shows that succinate from commensal bacteria promotes tuft cell development and reduces ileal inflammation in a mouse model of Crohn's disease.
bioRxiv · Sep 20, 2019Cell Biology