Author

A. J. Simmons

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

A. N. Southard-Smith· 2 shared B. Chen· 2 shared C. L. Sears· 2 shared J. T. Roland· 2 shared K. S. Lau· 2 shared M. J. Shrubsole· 2 shared M. K. Washington· 2 shared N. O. Markham· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. N. Southard-Smith

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Author profile →

3 papers

Recent·Most cited

Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors

B. Chen, E. T. McKinley, A. J. Simmons, M. A. Ramirez, X. Zhu, A. N. Southard-Smith, N. O. Markham, Q. Sheng, J. Drewes, Y. Xu, C. N. Heiser, Y. Zhou, F. Revetta, L. D. Berry, W. Zheng, , K. Lau

The paper creates a single-cell atlas of colorectal pre-cancerous polyps, identifying distinct molecular programs in adenomas and sessile serrated lesions and their associations with CRC subtypes.

bioRxiv · Jan 11, 2021Cancer Biology

Clinically adaptable polymer enables simultaneous spatial analysis of colonic tissues and biofilms

M. C. Macedonia, J. L. Drewes, N. O. Markham, A. J. Simmons, J. T. Roland, P. N. Vega, C. R. Scurrah, R. J. Coffey, M. J. Shrubsole, C. L. Sears, K. S. Lau

This paper introduces a clinically adaptable polymer that preserves spatial compartments of colonic tissues and biofilms for simultaneous analysis.

bioRxiv · Apr 15, 2020Cell Biology

Commensal-derived succinate enhances tuft cell specification and suppresses ileal inflammation

A. Banerjee, C. A. Herring, H. Kim, B. Chen, A. J. Simmons, A. N. Southard-Smith, J. R. White, M. A. Ramirez Solano, E. A. Scoville, Q. Liu, M. K. Washington, K. S. Lau

The paper shows that succinate from commensal bacteria promotes tuft cell development and reduces ileal inflammation in a mouse model of Crohn's disease.

bioRxiv · Sep 20, 2019Cell Biology