A DNA damage-induced phosphorylation circuit enhances Mec1ATR-Ddc2ATRIP recruitment to Replication Protein A.
L. A. Yates, E. A. Tannous, R. M. Morgan, P. M. Burgers, X. Zhang
This paper shows that phosphorylation enhances Mec1-Ddc2 recruitment to RPA-ssDNA, facilitating DNA damage checkpoint signaling in yeast.
bioRxiv · Dec 23, 2022 · PreprintBiochemistry