Author

E. B. Zheng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:deep learning· 2 Organism:Drosophila· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

L. Zhao· 4 shared S. Khodursky· 2 shared A. Gadau· 1 shared C. S. Jiang· 1 shared D. R. Schrider· 1 shared N. Svetec· 1 shared R. Vaughan· 1 shared S. Benjamin· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersEvolutionary Biology

L. Zhao

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Author profile →

4 papers

Recent·Most cited

The evolution and mutational robustness of chromatin accessibility in Drosophila

S. Khodursky, E. B. Zheng, N. Svetec, S. M. Durkin, S. Benjamin, A. Gadau, X. Wu, L. Zhao

This study uses deep neural networks to analyze chromatin accessibility in Drosophila, showing sequence determinants are conserved and accessibility is mutationally robust yet malleable under selection.

bioRxiv · Jun 26, 2023 · PreprintEvolutionary Biology

Sex differences in inter-individual gene expression variability across human tissues

S. Khodursky, C. S. Jiang, E. B. Zheng, R. Vaughan, D. R. Schrider, L. Zhao

The paper identifies sex-differentially variable genes across human tissues and links them to biological functions and disease, suggesting a genetic basis and evolutionary model for sex-specific expression variability.

bioRxiv · Aug 9, 2022Evolutionary Biology

Protein evidence of unannotated ORFs in Drosophila reveals unappreciated diversity in the evolution of young proteins

E. B. Zheng, L. Zhao

The paper identifies over 1000 unannotated open reading frames with protein evidence in Drosophila, revealing diverse evolutionary patterns and frequent turnover of de novo proteins.

bioRxiv · Apr 4, 2022Evolutionary Biology

Nonreciprocal and Conditional Cooperativity Directs the Pioneer Activity of Pluripotency Transcription Factors

S. Li, E. B. Zheng, L. Zhao, S. Liu

This study investigates the nonreciprocal and conditional cooperativity between Sox2 and Oct4 in nucleosome targeting using single-molecule fluorescence microscopy.

bioRxiv · May 9, 2019Biophysics