Nonionic surfactants can modify the thermal stability of globular and membrane proteins interfering with the thermal proteome profiling principles to identify protein targets
E. Berlin, V. Lizano-Fallas, A. Carrasco del Amor, O. Fresnedo, S. Cristobal
This paper shows that nonionic surfactants affect thermal stability of proteins, challenging thermal proteome profiling for membrane protein target identification.
bioRxiv · Oct 17, 2022Biophysics