Author

S. Cristobal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

V. Lizano-Fallas· 3 shared A. Carrasco del Amor· 2 shared A. Carrasco de Amor· 1 shared A. Cavalli· 1 shared A. J. Arribas· 1 shared A. Lupia· 1 shared A. M. Carrasco del Amor· 1 shared A. Stathis· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersPharmacology & Toxicology

V. Lizano-Fallas

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Predictive toxicology of chemical mixtures using proteome-wide thermal profiling and protein target properties

V. Lizano-Fallas, A. Carrasco de Amor, S. Cristobal

This paper introduces a method to predict the impact of chemical mixtures on health by identifying protein targets and analyzing their roles in cellular pathways.

bioRxiv · Jul 4, 2023Pharmacology & Toxicology

A first-in-class Wiskott-Aldrich syndrome protein (WASp) activator with anti-tumor activity in hematological cancers

F. Spriano, G. Sartori, L. Barnabei, A. J. Arribas, M. Guala, A. M. Carrasco del Amor, M. R. Tomasso, C. Tarantelli, L. Cascione, G. Golino, M. E. Riveiro, R. Bortolozzi, A. Lupia, F. Paduano, S. Huguet, , E. Gaudio

This paper develops EG-011, a first-in-class WASp activator with anti-tumor activity in hematological cancers, including resistant models.

bioRxiv · Nov 25, 2022 · PreprintCancer Biology

Proteome integral solubility alteration assay combined with multi-criteria decision-making analysis for developing adverse outcome pathways

V. Lizano-Fallas, A. Carrasco del Amor, S. Cristobal

This paper combines a proteome integral solubility alteration assay with multi-criteria decision-making analysis to identify suitable protein targets for developing adverse outcome pathways.

bioRxiv · Oct 17, 2022 · PreprintPharmacology & Toxicology

Nonionic surfactants can modify the thermal stability of globular and membrane proteins interfering with the thermal proteome profiling principles to identify protein targets

E. Berlin, V. Lizano-Fallas, A. Carrasco del Amor, O. Fresnedo, S. Cristobal

This paper shows that nonionic surfactants affect thermal stability of proteins, challenging thermal proteome profiling for membrane protein target identification.

bioRxiv · Oct 17, 2022Biophysics