Serum-mediated cleavage of Bacillus anthracis Protective Antigen is a two-step process that involves a serum carboxypeptidase
D. L. Goldman, E. Nieves, A. Nakouzi, J. Rivera, E. E. Phyu, T. H. Win, J. Achkar, A. Casadevall
The paper shows serum cleaves Bacillus anthracis Protective Antigen in two steps: first by splitting PA83 into PA63 and PA20, then removing terminal residues via carboxypeptidase.
bioRxiv · Feb 18, 2018Microbiology