Simultaneous selection of nanobodies for accessible epitopes on immune cells in the tumor microenvironment
T. V. Sekar, E. Elghonaimy, K. L. Swancutt, S. Diegeler, I. Gonzalez, C. Hamilton, P. Q. Leung, J. Meiler, C. E. Martina, M. Whitney, T. A. Aguilera
This study introduces INSPIRE-seq, a method to identify nanobodies targeting immune cells in the tumor microenvironment, revealing a dendritic cell-binding nanobody that interacts with PHB2.
bioRxiv · May 26, 2021Bioengineering