A single de novo substitution in SARS-CoV-2 spike informs enhanced adherence to human ACE2.
E. Erausquin, J. Lopez-Sagaseta
The paper identifies a single amino acid substitution in SARS-CoV-2 spike that enhances binding to human ACE2, with structural evidence supporting the increased affinity.
bioRxiv · Jul 16, 2021 · PreprintImmunology