Quantitative Assays Reveal Cell Fusion at Minimal Levels of SARS-CoV-2 Spike Protein and Fusion-from-Without
S. A. Theuerkauf, A. Michels, V. Riechert, T. J. Maier, E. Flory, K. Cichutek, C. J. Buchholz
The paper develops quantitative assays to study SARS-CoV-2 spike protein-mediated cell fusion, revealing that syncytia formation can occur at low S protein levels and is less inhibited by antibodies than particle-cell fusion.
bioRxiv · Oct 15, 2020Microbiology