Small Extracellular Vesicles from Failing Heart Accelerate Tumor Growth
T. Caller, I. Rotem, O. Shaihov Teper, D. Lendengolts, Y. Schary, R. Shai, E. Glick Saar, D. Dominissini, M. Motie, I. Katzir, R. Popovtzer, M. Nahmoud, A. Boomgarden, C. DSouza Schorey, N. Naftali Shani, J. Leor
This study shows that cardiac small extracellular vesicles from failing hearts promote tumor growth and that spironolactone treatment reduces this effect.
bioRxiv · Sep 3, 2023 · PreprintCancer Biology