High-content phenotypic screen to identify small molecule enhancers of parkin-dependent ubiquitination and mitophagy
R. Tufi, E. H. Clark, T. Hoshikawa, C. Tsagkaraki, J. Stanley, K. Takeda, J. M. Staddon, T. Briston
The paper identifies small molecule enhancers of parkin-dependent ubiquitination and mitophagy through a high-content phenotypic screen in patient-derived fibroblasts.
bioRxiv · Sep 30, 2022Cell Biology