Author

E. H. Hernandez

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Manglik· 1 shared R. Irannejad· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperCell Biology

A. Manglik

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1 paper

Recent·Most cited

Anionic phospholipids determine G protein coupling selectivity at distinct subcellular membrane compartments

E. H. Hernandez, A. Manglik, R. Irannejad

This study shows that anionic phospholipids like PI(4,5)P2 enable promiscuous GPCR coupling to both cognate and non-cognate G proteins at the plasma membrane, while restricting coupling to cognate G proteins in other compartments.

bioRxiv · Aug 31, 2023 · PreprintCell Biology