PRC2 bridges non-adjacent nucleosomes to establish heterochromatin
R. Leicher, E. J. Ge, X. Lin, M. J. Reynolds, T. Walz, B. Zhang, T. W. Muir, S. Liu
This study investigates how PRC2 interacts with chromatin using single-molecule force spectroscopy and simulations, revealing new binding configurations and their regulation.
bioRxiv · Oct 7, 2019Biophysics