Structural elucidation of the heterodimeric cis-prenyltransferase NgBR/DHDDS complex reveals novel insights in regulation of protein glycosylation
B. H. Edani, K. A. Grabinsko, R. Zhang, E. J. Park, B. Siciliano, L. Surmacz, Y. Ha, B. Sessa
The paper reports the crystal structure of the human NgBR/DHDDS complex, revealing how it stabilizes the active site and is regulated by phospholipids in protein glycosylation.
bioRxiv · Jun 3, 2020Biochemistry