A surface pocket in the cytoplasmic domain of the herpes simplex virus fusogen gB controls membrane fusion
Z. Pataki, E. K. Sanders, E. E. Heldwein
This paper identifies a surface pocket in the cytoplasmic domain of herpes simplex virus gB and a residue in gH that interact to release the inhibitory clamp on gB, activating membrane fusion.
bioRxiv · Mar 14, 2022Microbiology