STAT3 regulates cytokine production downstream of TNFR1 in part by inducing expression of TNFAIP3/A20
R. J. Antonia, E. Karelehto, K. Toriguchi, M. Matli, R. S. Warren, L. M. Pfeffer, D. B. Donner
This study shows STAT3 regulates cytokine production downstream of TNFR1 by inducing TNFAIP3/A20 expression, which limits inflammation, while also promoting GM-CSF expression.
bioRxiv · Jan 19, 2022 · PreprintCell Biology