Author

L. M. Pfeffer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Astrinidis· 1 shared D. B. Donner· 1 shared D. L. Johnson· 1 shared E. Karelehto· 1 shared E. Y. Zhang· 1 shared J. J. Bissler· 1 shared J. J. Yu· 1 shared K. Toriguchi· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Astrinidis

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Combination of Volasertib and Rapamycin Inhibits the Regrowth of TSC2-Deficient Tumors

M. Valianou, E. Y. Zhang, D. L. Johnson, R. Meyers, M. M. Markiewski, M. Karbowniczek, L. M. Pfeffer, J. J. Yu, J. J. Bissler, A. Astrinidis

This study shows that combining volasertib and rapamycin inhibits tumor regrowth in TSC2-deficient models more effectively than rapamycin alone.

bioRxiv · Nov 2, 2022 · PreprintCancer Biology

STAT3 regulates cytokine production downstream of TNFR1 in part by inducing expression of TNFAIP3/A20

R. J. Antonia, E. Karelehto, K. Toriguchi, M. Matli, R. S. Warren, L. M. Pfeffer, D. B. Donner

This study shows STAT3 regulates cytokine production downstream of TNFR1 by inducing TNFAIP3/A20 expression, which limits inflammation, while also promoting GM-CSF expression.

bioRxiv · Jan 19, 2022 · PreprintCell Biology