Highly potent photoinactivation of bacteria using a water soluble, cell permeable, DNA-binding photosensitizer
E. M. Digby, T. Ma, J. Milstein, A. A. Beharry
This paper demonstrates that Br-DAPI, a DNA-binding photosensitizer, effectively eradicates both gram-negative and gram-positive bacteria through ROS-mediated cell death at low concentrations and light doses.
bioRxiv · Jun 11, 2021Biophysics