The role of cytosolic polyadenylation element binding protein 2 alternative splicing in hypoxia
E. M. Mayo, S. C. Stevens, A. N. Ali, C. J. Moss, S. P. Lund, G. S. Nazario-Munoz, J. B. Permuth, S. D. Westerheide, C. E. Chalfant, M. A. Park
This study shows that CPEB2 alternative splicing regulates HIF1 translation during chronic hypoxia, with CPEB2B promoting translation and CPEB2A repressing it, and this pathway depends on eIF3H.
bioRxiv · Oct 5, 2020 · PreprintCell Biology