Multicomponent depolymerization of actin filament pointed ends by cofilin and cyclase-associated protein depends upon filament age
E. M. Towsif, B. A. Miller, H. Ulrichs, S. Shekhar
This study shows cofilin and CAP promote depolymerization of ADP-Pi actin filaments, though at lower rates than ADP filaments, suggesting new pathways for actin filament disassembly.
bioRxiv · Apr 15, 2024Biochemistry