ATP2, the essential P4-ATPase of malaria parasites, catalyzes lipid-dependent ATP hydrolysis in complex with a Cdc50 β-subunit
A. Lamy, E. Macarini-Bruzaferro, A. Peralvarez-Marin, M. le Maire, J. L. Vazquez-Ibar
This study investigates the function and structural organization of the malaria parasite ATP2, showing it forms a complex with Cdc50 proteins and catalyzes ATP hydrolysis in the presence of specific phospholipids.
bioRxiv · Jun 8, 2020Biochemistry