Missing the sweet spot: one of the two N-glycans on human Gb3/CD77 synthase is expendable
K. Mikolajczyk, A. Bereznicka, K. Szymczak-Kulus, K. Haczkiewicz-Lesniak, B. Szulc, M. Olczak, J. Rossowska, E. Majorczyk, K. Kapczynska, N. V. Bovin, M. Lisowska, R. Kaczmarek, A. Miazek, M. Czerwinski
This study shows that one N-glycan on human Gb3/CD77 synthase is essential for activity and localization, while the other is dispensable and even enhances activity.
bioRxiv · Feb 4, 2021Biochemistry