Hot-spots and their contribution to the self-assembly of the viral capsid: in-vitro validation
A. G. Valdez-Lara, M. Andrade-Medina, J. A. Aleman-Vilis, A. A. Perez-Montoya, N. Pineda-Aguilar, E. Martinez-Guerra, A. Roldan-Salgado, P. Gaytan, M. Carrillo-Tripp
This study validates in vitro the role of conserved interface residues as hot-spots in viral capsid self-assembly using point-mutations and thermal shift assays.
bioRxiv · Nov 15, 2019 · PreprintBiophysics