Pentapeptide repeat proteins QnrB1 and AlbG require ATP hydrolysis to rejuvenate poisoned gyrase complexes
L. Mazurek, D. A. Ghilarov, E. Michalczyk, Z. Pakosz, W. Czyszczon, K. Wawro, I. Behroz, R. D. Suessmuth, J. G. Heddle
This study investigates how QnrB1 and AlbG protect gyrase from poisons by requiring ATP hydrolysis, showing QnrB1 binds to GyrB and acts as a DNA mimic.
bioRxiv · Sep 24, 2020Biochemistry