Transient activation of the UPRER is an essential step in the acquisition of pluripotency during reprogramming
M. Simic, E. Moehle, R. Schinzel, F. Lorbeer, D. Jullie, J. Halloran, K. Heydari, M. Sanchez, D. Hockemeyer, A. Dillin
This study shows that transient activation of the UPRER is essential for successful reprogramming of somatic cells into pluripotency and can predict reprogramming efficiency.
bioRxiv · Nov 17, 2018Cell Biology