Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells
M. Stoeber, D. Jullie, J. Li, S. Chakraborty, S. Majumdar, N. A. Lambert, A. Manglik, M. von Zastrow
The paper develops a cell-based assay to study agonist-selective recruitment of engineered protein probes and GRK2 by opioid receptors in living cells, showing differential recruitment by distinct opioid ligands.
bioRxiv · Dec 5, 2019Cell Biology