α-catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity-dependence
A. Mukherjee, S. Melamed, H. Damouny-Khoury, M. Amer, L. Feld, E. Nadjer-Boger, M. P. Sheetz, H. Wolfenson
This study shows α-catenin links integrin adhesions to F-actin, regulating ECM mechanosensing and rigidity dependence through interactions with vinculin and effects on adhesion maturation and force transmission.
bioRxiv · Jan 21, 2021Cell Biology