Author

E. Rajakumara

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Biophysics· 1

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Approach:experimental assay· 1

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S. Abhishek· 1 shared W. Deeksha· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperBiophysics

S. Abhishek

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1 paper

Recent·Most cited

PAR recognition by PARP1 regulates DNA-dependent activities and independently stimulates catalytic activity of PARP1

W. Deeksha, S. Abhishek, E. Rajakumara

This study identifies PAR reader domains in PARP1 and reveals that PAR stimulates PARP1 catalytic activity while inhibiting DNA-dependent activity through an allosteric mechanism.

bioRxiv · Dec 21, 2021Biophysics