Oligomerization of the Human Adenosine A2A Receptor Is Driven by the Intrinsically Disordered C-Terminus
K. D. Nguyen, M. Vigers, E. Sefah, S. Seppala, J. P. Hoover, N. S. Schonenbach, B. Mertz, M. A. O'Malley, S. Han
This study identifies the intrinsically disordered C-terminus of the human A2A receptor as the driver of its homo-oligomerization through multiple interaction types.
bioRxiv · Dec 21, 2020Biophysics