The cytolethal distending toxin modulates cell differentiation and elicits epithelial to mesenchymal transition
L. AZZi-MARTIN, V. Touffait-Calvez, M. Everaert, R. Jia, E. Sifre, L. Seeneevassen, C. Varon, P. Dubus, A. Menard
This study shows that CdtB induces epithelial to mesenchymal transition in mouse and human cells, promoting cancer progression through increased cell motility and mesenchymal marker expression.
bioRxiv · Apr 6, 2022Microbiology