RNA-CLAMP Enables Photo-activated Control of CRISPR-Cas9 Gene Editing by Site-specific Intramolecular Cross-linking of the sgRNA
D. Zhang, S. Jin, L. Liu, E. Tota, Z. Li, X. Piao, N. K. Devaraj
RNA-CLAMP enables photo-activated control of CRISPR-Cas9 gene editing by clamping and photo-cleaving sgRNA stem loops to regulate activity.
bioRxiv · Apr 22, 2021 · PreprintBiochemistry