Single cell landscape of hypertrophic scars identifies serine proteases as key regulators of myofibroblast differentiation
V. Vorstandlechner, M. Laggner, D. Copic, Y. Chen, B. Golabi, W. Haslik, C. Radtke, E. Tschachler, H. J. Ankersmit, M. Mildner
The paper uses single-cell sequencing to analyze hypertrophic scars, identifying serine proteases as key regulators of myofibroblast differentiation and suggesting their inhibition for treating skin fibrosis.
bioRxiv · Jun 17, 2020 · PreprintCell Biology