TNFa-induced LDL cholesterol accumulation involve elevated LDLR cell surface levels and SR-B1 downregulation in human arterial endothelial cellsan arterial endothelial cells
This study shows TNF increases LDLR cell surface levels and reduces SR-B1 in human endothelial cells, leading to LDL cholesterol accumulation.
bioRxiv · Jun 29, 2020Biochemistry