Connexin 43 plays an important role in the transformation of human cholangiocytes upon stimulation with Clonochis sinensis excretory-secretory protein and N-nitrosodimethylamine
E.-M. Kim, S.-T. HONG, Y. M. Bae, M.-H. Choi
This study shows that Clonorchis sinensis excretory-secretory proteins and NDMA increase cholangiocyte proliferation and Cx43 expression, suggesting Cx43 as a potential target for cholangiocarcinoma prevention.
PLOS Neglected Tropical Diseases · Apr 3, 2019Peer-reviewedCancer Biology