Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity
Hamit İzgi, DingDing Han, Ulas Isildak, Shuyun Huang, Ece Kocabiyik, Philipp Khaitovich, Mehmet Somel, Handan Melike Dönertaş
The paper analyzes gene expression in multiple tissues across development and ageing in mice, finding that tissues converge in expression patterns with age, associated with loss of tissue identity.
eLife · Jan 31, 2022Peer-reviewedGenomics