Author

Edward P. Gniffke

Seattle Children's Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:cell-cell communication· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Jonathan D. LautziD· 3 shared Stephen E.P. SmithiD· 3 shared John P. WelshiD· 2 shared Karen B. ImmendorfiD· 2 shared Emily A. BrowniD· 1 shared Haley E. SpeediD· 1 shared Kaleb B. TsegayiD· 1 shared Ryan D. MendeliD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Jonathan D. LautzORCID

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3 papers

Recent·Most cited

Synaptic signaling networks encode experience by assuming stimulus-specific and brain-region-specific states

Jonathan D. Lautz, Kaleb B. Tsegay, Zhiyi Zhu, Edward P. Gniffke, John P. Welsh, Stephen E.P. Smith

The paper identifies stimulus-specific and brain-region-specific synaptic protein interaction network dynamics during learning tasks.

Cell Reports · Nov 1, 2021Peer-reviewedNeuroscience

Homeostatic Plasticity Requires Remodeling of the Homer-Shank Interactome

Whitney E. Heavner, Haley E. Speed, Jonathan D. Lautz, Edward P. Gniffke, Karen B. Immendorf, John P. Welsh, Stephen E.P. Smith

The paper investigates how homeostatic plasticity alters synaptic protein interactions, showing that Homer1 and Shank3B are critical for structural rearrangements during synaptic scaling.

bioRxiv · Mar 26, 2020 · PreprintNeuroscience

Activity-dependent changes in synaptic protein complex composition are consistent in different detergents despite differential solubility

Jonathan D. Lautz, Edward P. Gniffke, Emily A. Brown, Karen B. Immendorf, Ryan D. Mendel, Stephen E.P. Smith

The paper examines how different detergents affect activity-dependent synaptic protein interactions and finds that while detergent solubility varies, activity-dependent changes in protein complexes are consistent across detergents.

Scientific Reports · Jul 26, 2019Peer-reviewedNeuroscience