Loss of SUR1 subtype KATP channels alters antinociception and locomotor activity after opioid administration
Gerald Sakamaki, Kayla Johnson, Megan E. Mensinger, Eindray Hmu, Amanda H. Klein
This study investigates the role of SUR1-subtype KATP channels in opioid-induced antinociception and hyperlocomotion, finding attenuated antinociception and potentiated hyperlocomotion in SUR1-deficient mice.
Behavioural Brain Research · Jul 15, 2021Peer-reviewedNeuroscience