Notch1 and Notch2 receptors mediate the prosensory functions of the Notch ligand Jagged1 in the mammalian cochlea
He Huang, Xiaojun Li, Elannah Venhaus, Angelika Doetzlhofer
This study identifies Notch1 and Notch2 as mediators of Jagged1's prosensory functions in the cochlea by showing their role in maintaining prosensory progenitors and regulating cell-cycle exit and innervation.
bioRxiv · Oct 5, 2026 · PreprintDevelopmental Biology