The emergence of human gastrulation upon in vitro attachment
Riccardo De Santis, Eleni Rice, Gist F. Croft, Min Yang, Edwin A. Rosado-Olivieri, Ali H. Brivanlou
This study shows human blastoids undergo gastrulation upon in vitro attachment, replicating the transcriptomic signature of natural human gastrula and suggesting an earlier onset of gastrulation than previously thought.
bioRxiv · May 16, 2023 · PreprintDevelopmental Biology